Blow-fill-seal machines are advanced packaging systems used in the pharmaceutical and healthcare industries to produce small, single-dose containers. These machines combine the processes of blow molding, filling, and sealing into one continuous operation, resulting in a highly efficient and sterile packaging solution. Primary packaging refers to the individual containers that hold the product, while secondary packaging refers to the outer packaging that holds multiple primary containers together. In the case of blow-fill-seal machines, the primary packaging is the small, sealed containers that are directly filled with the product. The secondary packaging could be a box or carton that holds multiple primary containers for distribution and retail purposes. Blow-fill-seal machines work by first blowing a plastic tube into a mold to create the container shape. The container is then filled with the product, such as liquid medication or eye drops, before being sealed to ensure sterility. This process is highly automated and can produce a large number of containers quickly and efficiently. Overall, blow-fill-seal machines offer a cost-effective and reliable packaging solution for pharmaceutical and healthcare products, ensuring product integrity and safety throughout the supply chain.