Capsule sizes are systematically numbered from largest to smallest, with size 000 being the largest and size 5 the smallest. The size of a capsule directly correlates with its volume and weight capacity. For instance, size 000 capsules have a volume of approximately 1.37 ml and can hold up to 1370 mg, whereas size 5 capsules have a volume of 0.13 ml and a capacity ranging from 100 to 150 mg. The exact weight capacity is influenced by the density of the powder being encapsulated. Below is a detailed table outlining the various capsule sizes, their approximate volumes, weight capacities, and common uses: 

Capsule Size Approximate Volume (ml) Approximate Weight Capacity (mg) Common Use
000 1.37 950 - 1370 High dosage supplements
00 0.95 665 - 950 General purpose for supplements
0 0.68 475 - 665 Smaller dosages, easy-to-swallow option
1 0.50 350 - 475 Lower dosage supplements
2 0.37 250 - 350 Moderate dosage
3 0.30 200 - 300 Small dosage
4 0.21 150 - 200 Very small dosage
5 0.13 100 - 150 Microdosing, children, or smaller animals